Tirzepatide is an innovative peptide designed to support metabolic regulation and weight management. Each vial contains 10 mg of high-purity Tirzepatide
$109
Tirzepatide is a synthetic 39-amino-acid peptide and the first dual GIP and GLP-1 receptor co-agonist to be characterised in metabolic research. Also referenced by the research alias GLP2-T, it is studied for its effects on glucose regulation, appetite signalling and body-weight endpoints. This listing is for a lyophilised research-grade vial supplied for laboratory and research use only.
Unlike single-pathway GLP-1 agonists, tirzepatide activates two incretin receptors at once — the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor. In published pharmacology it behaves as an “imbalanced” agonist: potency at the GIP receptor is close to that of native GIP, while its GLP-1 receptor activity is comparatively weaker and biased toward cAMP signalling. A C20 fatty-diacid moiety promotes albumin binding, which is what extends its circulating half-life. Together these pathways are associated in study models with improved insulin sensitivity, glucagon suppression and reduced food intake.
Tirzepatide has an approximate 120-hour (~5-day) half-life, driven by its albumin-binding fatty-diacid tail. In clinical study protocols this long half-life supported once-weekly administration. The extended exposure profile is one of the properties that distinguishes it from shorter-acting peptides in the same class.
Lyophilised tirzepatide is stable for extended periods when kept cold: roughly 24+ months at −20°C and 12–24 months at 2–8°C. For reconstitution, laboratories typically use bacteriostatic water (0.9% benzyl alcohol), which preserves the solution for multi-draw research over about 28 days when refrigerated at 2–8°C. Best practice noted in the literature: let a cold vial reach room temperature for 15–30 minutes before opening to avoid condensation, add diluent slowly against the vial wall rather than directly onto the powder, and do not freeze a reconstituted vial — freeze-thaw cycles degrade the peptide chain and reduce potency.
The information below describes published clinical-trial protocols and is provided for research context only — it is not a dosing recommendation. In the SURPASS and SURMOUNT programmes, administration began at 2.5 mg weekly and was escalated by 2.5 mg roughly every four weeks toward maintenance doses of up to 15 mg weekly. Slow titration was the single most effective strategy for limiting gastrointestinal side effects during dose escalation.
In clinical research, tirzepatide’s most frequently reported adverse events were gastrointestinal — nausea, diarrhoea, vomiting and constipation. Nausea was reported by roughly 24% of participants across the 5–15 mg doses versus about 9.5% on placebo. The majority of events were mild to moderate, occurred most often during the first weeks of dose escalation, and declined over time at each maintenance dose. These are research observations, not a safety profile for any non-clinical use.
The three most-studied incretin peptides differ by the number of receptors they target:
For research comparisons within the same class, see Retatrutide 10mg and the higher-capacity Retatrutide 40mg Pen & Kit. Peptides studied for different endpoints include the recovery-focused BPC-157 & TB-500 blend, IGF-1 LR3 1mg, and HCG 5000 IU.
Every batch we stock is intended to meet a ≥99% HPLC purity standard. Independent quality verification for research peptides centres on reversed-phase HPLC purity, mass-spectrometry identity confirmation and an assay result expressed as mg per vial. A batch Certificate of Analysis (COA) is available on request, and our published third-party HPLC lab reports document our wider third-party testing programme. We do not make therapeutic claims — quality here means verified identity and purity for laboratory work.
KGEAR U.S supplies research-grade tirzepatide with discreet, tracked shipping and crypto checkout. Browse the full peptides collection for related GLP-1, recovery and metabolic research peptides, including Melanotan-II (MT-2). All compounds are sold strictly for research use only.
Tirzepatide is the peptide compound studied in those clinical programmes. This listing is a research-grade lyophilised vial supplied for laboratory use, not a branded pharmaceutical product.
Our target specification is ≥99% purity verified by reversed-phase HPLC, with a batch COA available on request.
It activates both the GIP and GLP-1 receptors, whereas semaglutide activates only GLP-1. See the comparison section above.
Approximately 120 hours (~5 days), which in clinical studies supported once-weekly dosing.
Cold and dry before reconstitution (−20°C for long-term, 2–8°C shorter-term). After reconstitution with bacteriostatic water, refrigerate at 2–8°C and do not freeze.
Retatrutide is a triple agonist with higher weight-loss figures in early trials but remains investigational; tirzepatide is the more extensively studied dual agonist.
Yes — a batch COA is available on request, and our third-party HPLC lab reports page documents our testing programme.
No. All products are supplied strictly for laboratory and research use only, not for human or veterinary consumption.
This product is sold for laboratory and research use only. It is not a drug, food or supplement, and is not intended to diagnose, treat, cure or prevent any disease, nor for human or animal consumption. All efficacy, mechanism and dosing information above is a summary of published clinical research provided for scientific context only and is not medical advice. Handling of research compounds is the sole responsibility of the qualified purchaser.
This product is intended for research or educational purposes only and is not approved for human use unless prescribed by a licensed healthcare professional. Always consult a medical expert before beginning any supplement or hormone program.
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